The herb is found throughout the semitropical and tropical parts of india. In traditional systems of medicine, different parts leaves, stem, flower, root, seeds and even whole plant of ocimum sanctum linn known as tulsi in hindi, a small herb seen throughout india, have been recommended for the treatment of bronchitis, bronchial. Tulsi the wonder herb pharmacological activities of ocimum. The immunomodulatory activity were studied in wistar strain rats by the following parameters like delayed type. Pdf pharmacological activities of ocimum sanctum tulsi.
The lamiacae, or mint family, is a family of herbs, shrubs, and trees comprising about 200 genera and 3200 species, many with a long history of medicinal and food use university of hawaii, 2014. Review article pharmacological activities of ocimum. Phytochemical analysis, antibacterial and antioxidant activity. Holy basil herb seeds ocimum sanctum seed needs llc. Ocimum sanctum has been used in india for around 5000 years and is acclaimed for its healing properties of the mind, body and spirit 2, 3. The aqueous extract of ocimum sanctum at the dose rate of 100mg kg an 200 mgkg per orally exhibited significant protection against ethanol induced gastric ulceration. As it has been shown that tulsi exhibit anticancer activity in animal models. Josephs college, trichirappalli620 002, tamil nadu, india issued 15 december 2008 abstract ocimum sanctum, commonly known as sacred basil or holy basil, is grown as a household plant in. Ocimum is a genus of about 68 different species of aromatic annual and perennial herbs and shrubs in the family of lamiaceae, native of a tropical region. Antioxidant activity in ocimum sanctum linn, ocimum bascilicum. Ethanolic extract of ocimum sanctum leaves reduced. The use of plants as sources of medicines are human substance has been in vogue since antiquity. Mar 07, 2016 know about homeopathic medicine ocimum sanctum in homeopathy, the mother tincture of tulsi is available as homeopathic remedy, ocimum sanctum tincture in 2x, 3x, 6c potency. Leaves have petiole and are ovate, up to 5 cm long, usually somewhat toothed.
Antioxidant activity in ocimum sanctum linn, ocimum bascilicum and tpc or absorbance decrease of blank for abts and dpph values extract was substituted by demonized water for blank. Tulsi is pungent and bitter in taste, pungent in the post digestive effect and has hot potency. Ocimum tenuiflorum synonym ocimum sanctum, commonly known as holy basil or tulsi, is an aromatic perennial plant in the family lamiaceae. Holy basils potential anticancer activity and its ability to mitigate the negative ishii n. Pharmacological evaluation of ocimum sanctum longdom. Ocimum sanctum is an annual herb belonging to the mint family with 150 varieties worldwide. The present investigation revealed thatocimum sanctum exhibited significant antiulcer activity by enhancing antioxidant potential of gastric mucosa thereby reducing mucosal damage. Therapeutic uses of ocimum sanctum linn tulsi with a note. University department of pharmaceutical sciences, u. Antibacterial activity of aqueous, ethanol and acetone. The present study was conducted to elucidate the effects of the fixed oil extracted from os leaves on the blood glucose levels and serum lipid profile of streptozotocin. Ob that grown in madina province, western region, saudi arabia was investigated.
May 17, 2016 antibacterial activity of essential oil of ocimum sanctum l. Aqueous, ethanol and acetone leaf and root extracts of ocimum sanctum linn were investigated for their antibacterial activities at various concentrations against escherichia coli, staphylococcus aureus and pseudomonas aeruginosa using standard methods. To determine if tulsi ocimum sanctum extract has an antimicrobial activity against streptococcus mutans and to determine which concentration of tulsi ocimum sanctum extract among the 15 concentrations investigated has the maximum antimicrobial activity. Ocimum sanctum indian holy basiltulsi sunita verma abstract oscimum sanctum commonly known as tulsi, belong to lamiaceae family. The holy tulsi, also known as the queen of herbs is the most sacred of all the herbs found in india. Pharmacological activities of ocimum sanctum tulsi. Holy basil ocimum sanctum or ocimum tenuiflorum is a perennial species grown for ornamental and. Therapeutic uses of ocimum sanctum linn tulsi with a note on eugenol and its pharmacological actions. Antimicrobial activity of ocimum sanctum extract was carried out using well. Antioxidant activity in ocimum sanctum linn, ocimum. He concluded that it may be due to the activity on gaba energic pathways. Ocimum tenuiflorum, also called ocimum sanctum, holy basil, or tulasi, is associate degree aromatic plant within the labiatae that is native to the indian landmass and widespread as a tracheophyte throughout the southeast asian tropics.
Evaluation of the antiinflammatory activity of ocimum sanctum linn tulsi in albino rats mrutyunjay m mirje1, sameer uz zaman2, and s. The medicinal plants are widely used by the traditional medical practitioners for curing various diseases in their day to day practice. Keywords ocimum sanctum, expectorant, stimulant, anthelmentic. The proximate, minerals and preliminary phytochemical analysis of ocimum sanctum leaves were studied. Flowers are purplish in elongate racemes in close whorls. Tulsis broadspectrum antimicrobial activity, which includes activity against a range of. This name is a synonym of ocimum tenuiflorum l the record derives from wcsp data supplied on 20120323 which reports it as a synonym record 7068 with original publication details. Columbia institute of pharmacy, tekari, raipur, cg493 111 2. Hind agricultural research and training institute antioxidant activity and phenolic contents in ocimum sanctum and ocimum bascilicum inampudi sailaja1, ivvala anand shaker2 and yedlapalli keerthi ratna1 1department of biochemistry and molecular biology, college of agricultural biotechnology, loni,ahmednagar, m. Preliminary phytochemical studies and antibacterial activity of ocimum sanctum l. Therapeutic uses of ocimum sanctum linn tulsi several medicinal properties have been attributed to ocimum sanctum l. Qualitative phytochemical screening and gcms analysis of. Department of science and laboratory technology, dar es salaam institute of technology, dar es salaam, tanzania.
Tulsi the wonder herb pharmacological activities of. This sacred plant was found in almost every indian household. Leaves and flowering tops are used for extracting essential oil. Its genus ocimum contains more than 150 species and is considered one of the largest genera of its family, lamiaceae mints. Study of pharmacological effect of ocimum basilicum. Comprehensive evaluation of in vitro antioxidant activity, total phenols and chemical profiles of two commercially important strawberry varieties. Anticancer activity of ocimum sanctum article pdf available in pharmaceutical biology 374. Antidiabetic and antioxidative activity of fixed oil. The present investigation revealed that the antidiabetic activity of ethanolic extract of ocimum sanctum linn. Holy basil is known to be a sacred herb to the hindu people. Ocimum sanctum commonly known as tulsi in hindi and holy basil in english a popular herb was used for this study. Ethanopharmacological and phytochemical aspects of ocimum sanctum linn the elixir of life baby joseph 1, vrundha m.
Such research activities could also lead to the development of new drugs as in the. It is native to the indian subcontinent and widespread as a cultivated plant throughout the southeast asian tropics. Antioxidant activity and phenolic contents in ocimum sanctum. Both humoral and cell mediated immune response of ocimum sanctum seed oil was proved by mitra et al. Eugenol 1hydroxy2methoxy4allylbenzene, the active constituent present in ocimum sanctum l. Of all the herbs used within ayurveda, tulsi ocimum sanctum linn is. It is native to the indian subcontinent and widespread as a cultivated plant throughout the southeast asian tropics tulsi is cultivated for religious and traditional medicine purposes, and for its essential oil. Chemistry and bioactivities of essential oils of some ocimum. Page 1 queen of herbs tulsi ocimum sanctum removes impurities from water and plays disinfectant role babita labh kayastha 1 1.
Nair 1,2 1interdisciplinary research centre, department of biotechnology, malankara catholic college, mariagiri, kaliakkavilai 629 153, kanyakumari district, tamil nadu, india. Evaluation of invitro antioxidant and antiinflammatory. Extracts and standard drug were administered orally for 14 days. Evaluation of antidiabetic and antihyperlipidemic effects. Ocimum sanctum linn is the most prominent species of the genera. Evaluation of the antiinflammatory activity of ocimum. Introduction tulsi is an important symbol of the hindu religious. The highest larval mortality was found in leaf extract of o. Evaluation of some chemical composition, minerals fatty acid. Ethanopharmacological and phytochemical aspects of ocimum. Therefore, the present study was aimed to investigate the analgesic and antiinflammatory effects of the leaves of ocimum sanctum in laboratory animals. Review article chemical constituents and pharmacological.
The role of silver nanoparticles agnps is an attractive proposition for advancing modern diabetes therapies and applied science. But the scientific basis for its medicinal use especially in pain and inflammation remains unknown. Evaluation of invitro antioxidant and antiinflammatory activities of extract of ocimum sanctum linn t. Chemistry and bioactivities of essential oils of some. Antioxidant activity and phenolic contents in ocimum. Ethanopharmacological and phytochemical aspects of. Evaluation of antioxidant activity and neuroprotective property of extract of ocimum sanctum, linn 4. Nov 06, 2015 antibacterial activity of aqueous, ethanol and acetone extracts of ocimum sanctum linn. Invasion and matrix metalloproteinase activity of head and. Additionally, their total phenolic contents were analyzed by folinciocalteau micro method. The leaves are anise scented and can be used in tea, or as a potpourri. Grow a garden filled with holy basil herbs, from freshly harvested ocimum sanctum herb seeds. This family includes some of the most wellknown herbs containing essential oils including lavender, sage, basil, mint and oregano. Two type of ocimum sanctum are met within cultivation i.
Therapeutic uses of ocimum sanctum linn tulsi several medicinal properties have been attributed to ocimum sanctum. Therapeutic potential of ocimum sanctum in prevention and treatment of cancer. Know about homeopathic medicine ocimum sanctum homoeopathy. Research article ethanolic extract of ocimum sanctum leaves. Pdf evaluation of antidiabetic activity of ethanolic. Diffusion method by comparing the clear inhibition zone of standard. Comprehensive evaluation of in vitro antioxidant activity, total phenols and chemical profiles. Evaluation of antidiabetic activity of ethanolic extract of ocimum sanctum linn. The leaves of the plant are considered to be very holy and often form a consistent part of the hindu spiritual rituals tirtha or prasada. Therapeutic uses of ocimum sanctum linn tulsi with a. The antioxidant activity of a methanolic extract of ocimum basilicum l.
The acetone, chloroform, ethyl acetate, hexane, and methanol leaf and flower extracts of ocimum sanctum were studied against fourth instar larvae of aedes aegypti and culex quinquefasciatus. Antimicrobial studies indicated that both the acetone leaf and root extracts of o. Evaluation of some chemical composition, minerals fatty. Evaluation of the antimicrobial activity of various. To evaluate the immunomodulatory activity of aqueous leaf extract of ocimum sanctum aleos by invitro and invivo methods. It clears the mind, stabilizes the blood sugar levels and sooths the chest conditions. Review article pharmacological activities of ocimum sanctum. It is believed to purify expectorants, and called the wonder herb. Medicinal plant tulasi and its uses open access journals. Ocimum taxonomy, medicinal potentialities and economic. Medicinal properties, ocimum sanctum os, tulsi, pharmacological activities. The immunomodulatory activity were studied in wistar strain rats by the following parameters like delayed type hypersensitivity dth, humoral antibody titre. Pdf enhancing antidiabetic and antimicrobial performance.
Ocimum sanctum is a plant with enormous properties for curing and preventing diseases. Ocimum sanctum, known as tulsi in hindi and holy basil in english, is an erect softy hairy aromatic herb or undershurb found throughout india. The genus ocimum includes a variety of herbs and shrubs, including several species of basil. Efficacy of ocimum sanctum for relieving stress the journal of. The results showed that one rosmarinic acid can capture 1. Singh et al biological activities of ocimum sanctum l. It concluded that, ob and ml extracts have the potency to act as powerful antioxidants and protect against dna. Evaluation of antiulcer activity of ocimum sanctum in rats. Stable agnps with a size range of 325 nm were synthesized using aqueous leaf extracts from ocimum basilicum, ocimum. Os leaves have been shown to exert diverse potential benefits in a variety of stress conditions. Phytochemical screening and antibacterial activities of.
Evaluation of antidiabetic activity of ethanolic extract. Holy basil plants will mature to a height of roughly 18 to 20 inches tall, and can. The study deals with the efficacy of ocimum sanctum essential oil eo and its major component, eugenol against the fungi causing biodeterioration of food stuffs during storage. Labiateae or lamiaceae comprises 30 species which are found in tropical and subtropical regions. Immunomodulatory activity of aqueous leaf extract of. Immunomodulatory activity of aqueous leaf extract of ocimum. Fixed oil 405 prostaglandin synthesis could help to explain their antipyretic activity12. Antibacterial activity of essential oil of ocimum sanctum l. Ramabhimaiah3 1dept of pharmacology, institute of medical science and research, mayni, tal katva, satara415102, india 2kamineni academy of medical science and research centre, l. Basils are native to tropical asia, though many varieties grow wild in various areas of asia and africa. Ocimum sanctum is perhaps the most common and most revered of all household plants in india. Different parts of the plant are used of many illnesses like cough, influenza, axonomy, traditionally used and various pharmacological activity study of the plant. Phytochemical analysis the various extracts and fractions of ocimum. Often referred to as tulsi, these herbs have been consumed to improve immune health.
Ocimum sanctum has been described as of two types i. Chemical composition, antifungal and antiaflatoxigenic. Ocimum sanctum possess significant antistress activity but. Antimicrobial activity of tulsi ocimum tenuiflorum. Preliminary phytochemical studies and antibacterial. The nutritional analysis of ocimum sanctum shown high level of ascorbic acid and total carbohydrate i. Shashikala 2 1department of pharmacology, sri venkateshwara medical college hospital and research. The anticancer activity and antioxidative potentials of methanolic extracts of mentha longifolia l. Antioxidant activity and phenolic contents in ocimum sanctum and ocimum bascilicum inampudi sailaja1, ivvala anand shaker2 and yedlapalli keerthi ratna1 1department of biochemistry and molecular biology, college of agricultural biotechnology, loni,ahmednagar, m.
277 603 852 1116 83 781 471 1139 1358 263 494 97 861 1463 1521 873 1308 825 353 549 955 1065 1183 356 496 36 1442 756 561 1471 1186 986 399 1080 1052 576 1030